Research Areas

Research Areas

NYCNMR has identified the following unmet medical needs and new applications:
 
• Delivery system for PNS (treatment of 650 orphan and neurodegenerative disorders)
• Traumatic Brain Injuries
• New drug delivery or release systems
• Liposomal drug base (suspension drug)
• Regenerative medicine applications
• Medical coating for medical application
• Toxicology reduction applications
• Anti-infectious applications
• Theranostics
 

Applications in Nanomedicine Therapeutics Diagnostics & Imaging Regenerative Medicine
Cardiovascular Diseases

Implantable devices (nano surface modification)

Targeted drug delivery into plaques

Nanoparticles for theranostic approaches

Intelligent bioactive materials

Stem cell mobilisation and homing at site of injury

Neurodegenerative Diseases

Semi invasive nanodevices for drug delivery (for Parkinson)

Nanoformulations for crossing the BBB and BNB.

Image guided implantation of advanced neurostimulators

Site specific delivery of neuroactive molecules

Intelligent biomaterials controlling CNS regeneration

Diabetes Insulin measurement and delivery by nano enabled devices

Encapsulation and monitoring of labelled islet transplants

Whole body imaging of fat distribution with nanoparticles

Implanted non-invasive continuous glucose monitoring

Functionalization of 2D and 3D materials for time and spatial release of biochemical factors for artificial pancreas
Cancer

New nano formulations for targeting agents to tumors

RF-heatable Nanoparticles for thermal therapy

Implantable devices for localized delivery of drugs

New therapeutic tools with physical mode of action

Monitoring of therapeutic efficacy

Nanoparticle tracers and contrast agents for diagnosis (Magnetic Particle Imaging)

Composite nanoparticles for monitoring of therapy

Minimal invasive endoscope / catheter for diagnostics and therapy

Nanostructured surfaces for biosensors

Functionalized nanoparticles for targeted in vivo activation of hematopoietic stem cell production
Inflammation

Soft nanomaterials for bone regeneration, Rheumathoid Arthritis and Crohn’s disease

Bacterial free nanomaterials to avoid infection by implanted materials

Imaging of nanoparticle labelled white cells

3D Nanomaterials for stem cell immobilisation at site of injury

Novel implant materials and surfaces to prevent implant infections

 
 

NANOMEDICINE 2020 Contribution of Nanomedicine to Horizon 2020 – White Paper to the Horizon 2020 Framework Programme for Research and Innovation – Recommendations from the Nanomedicine Community